{"id":3268,"date":"2022-10-05T14:46:49","date_gmt":"2022-10-05T14:46:49","guid":{"rendered":"https:\/\/drdimolenis.gr\/pathological-conditions-and-diseases-related-to-the-female-cycle\/"},"modified":"2026-03-24T10:09:10","modified_gmt":"2026-03-24T10:09:10","slug":"pathological-conditions-and-diseases-related-to-the-female-cycle","status":"publish","type":"post","link":"https:\/\/drdimolenis.gr\/en\/pathological-conditions-and-diseases-related-to-the-female-cycle\/","title":{"rendered":"Pathological conditions and diseases related to the female cycle"},"content":{"rendered":"

Beyond that, there are about 20 diseases and conditions that show a similar correlation. Of greatest interest are migraines and epilepsy.<\/p>\n

“Menstrual” migraine<\/strong><\/p>\n

Migraine affects women more than men and is more severe in women. 25% of women of reproductive age suffer from migraines. A number of women experience a worsening of their migraines during their periods. 34 to 60% of women with migraines have episodes around their periods, while only 7-10% have episodes exclusively during their periods. It is mainly the type of migraine without aura (symptoms that precede the episode) that shows a cycle-related pattern.<\/p>\n

Migraine often improves during pregnancy, but there are also women in whom migraine first appears during pregnancy. A percentage of women have an increased frequency of episodes during the perimenopausal period. After menopause, an improvement is observed, especially of migraine without aura. Hormone replacement therapy in menopause may bring back migraine. These data indicate the association of this condition with changes in hormone levels.<\/p>\n

The treatment initially includes the more intensive use of classic preparations during the days of worsening migraines. In more severe cases, we will consider suppressing ovulation with special injections, but unfortunately not with contraceptives, whose effect is difficult to predict: 36% of women will see improvement with contraceptives, in 46% the situation will remain the same while in 18% we will have a deterioration. In addition, the combination of migraine and contraceptives has a serious complication which is the increase in the risk of stroke. The presence of migraine alone increases the risk of stroke in women, while the combination of migraine with aura and contraceptives increases the risk of stroke by 12 times! If the woman is also a smoker, the risk increases further. For this reason, contraceptives are contraindicated in migraine with aura.<\/p>\n

Epilepsy<\/strong><\/p>\n

A number of women suffer from menstrual-related epilepsy. The exact percentage is difficult to determine, as a cyclical pattern cannot be identified when we have 1 to 2 episodes per month. In older studies, however, when the newer, better antiepileptic drugs were not available, one could see a clear cyclical pattern in many women of reproductive age, with a higher frequency of episodes at two specific points in time: 1) during the period and 2) just before ovulation (when estrogen levels are very high). In contrast, after ovulation, when progesterone levels are high, we have fewer episodes. This suggests that during the second phase of the cycle some unknown antiepileptic factor is present.<\/p>\n

There has been some discussion about whether we could reduce the episodes by suppressing ovulation with birth control pills. Unfortunately, this is not possible because one of their ingredients, the progestogen, has the opposite effect of suppressing natural progesterone. What has been shown to work well is a specific progesterone derivative that can be given as an injection every 3 months in cases where there is a clear correlation of the epileptic episodes with the changes in the cycle.<\/p>\n

This article was published in the magazine \u201cArt of Life and Health\u201d of the Health Group<\/p>\n","protected":false},"excerpt":{"rendered":"

The female cycle is characterized by fluctuations in sex hormones throughout its duration. These changes affect all organs of the body, including the brain, which has receptors for female hormones. The most well-known and common condition related to hormonal changes in the cycle is premenstrual syndrome. <\/p>\n","protected":false},"author":1,"featured_media":3269,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3268","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-1"],"yoast_head":"\nPathological conditions and diseases related to the female cycle - \u039b\u03ac\u03bc\u03c0\u03c1\u03bf\u03c2 \u0399. \u0394\u03b7\u03bc\u03bf\u03bb\u03ad\u03bd\u03b7\u03c2, MD, MSc<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/drdimolenis.gr\/en\/pathological-conditions-and-diseases-related-to-the-female-cycle\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pathological conditions and diseases related to the female cycle - \u039b\u03ac\u03bc\u03c0\u03c1\u03bf\u03c2 \u0399. \u0394\u03b7\u03bc\u03bf\u03bb\u03ad\u03bd\u03b7\u03c2, MD, MSc\" \/>\n<meta property=\"og:description\" content=\"The female cycle is characterized by fluctuations in sex hormones throughout its duration. 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